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Cardiopulmonary phenotype associated with human PHD2 mutation
Oxygen‐dependent regulation of the erythropoietin gene is mediated by the hypoxia‐inducible factor (HIF) family of transcription factors. When oxygen is plentiful, HIF undergoes hydroxylation by a family of oxygen‐dependent prolyl hydroxylase domain (PHD) proteins, promoting its association with the...
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| Publicado no: | Physiol Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5392514/ https://ncbi.nlm.nih.gov/pubmed/28400504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13224 |
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