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Metabolic interrogation as a tool to optimize chemotherapeutic regimens

Platinum-based (Pt) chemotherapy is broadly utilized in the treatment of cancer. Development of more effective, personalized treatment strategies require identification of novel biomarkers of treatment response. Since Pt compounds are inactivated through cellular metabolic activity, we hypothesized...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sandulache, Vlad C., Chen, Yunyun, Feng, Lei, William, William N., Skinner, Heath D., Myers, Jeffrey N., Meyn, Raymond E., Li, Jinzhong, Mijiti, Ainiwaer, Bankson, James A., Fuller, Clifton D., Konopleva, Marina Y., Lai, Stephen Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392315/
https://ncbi.nlm.nih.gov/pubmed/28184025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15186
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