3’-hydroxy-4’-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction

The β-nitrostyrene family has been shown to suppress cell proliferation and induce apoptosis in types of various cancers. However, the mechanisms underlying the anticancer effects of β-nitrostyrenes in colorectal cancer remain poorly understood. In this study, we synthesized a β-nitrostyrene derivat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tsai, Chun-Hao, Hung, Amos C., Chen, Yuan-Yin, Chiu, Ya-Wen, Hsieh, Pei-Wen, Lee, Yi-Chen, Su, Yu-Han, Chang, Po-Chih, Stephen Chu-Sung, Hu, Yuan, Shyng-Shiou F.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392311/
https://ncbi.nlm.nih.gov/pubmed/28178649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14996
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