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A novel cell-penetrating peptide suppresses breast tumorigenesis by inhibiting β-catenin/LEF-1 signaling

The inhibition of β-catenin/LEF-1 signaling is an emerging strategy in cancer therapy. However, clinical targeted treatment of the β-catenin/LEF-1 complex remains relatively ineffective. Therefore, development of specific molecular targets is a key approach for identifying new cancer therapeutics. T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hsieh, Tsung-Hua, Hsu, Chia-Yi, Tsai, Cheng-Fang, Chiu, Chien-Chih, Liang, Shih-Shin, Wang, Tsu-Nai, Kuo, Po-Lin, Long, Cheng-Yu, Tsai, Eing-Mei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707489/
https://ncbi.nlm.nih.gov/pubmed/26750754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19156
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