Atorvastatin inhibits the immediate-early response gene EGR1 and improves the functional pro of CD4(+)T-lymphocytes in acute coronary syndromes

Background- Adaptive immune-response is associated with a worse outcome in acute coronary syndromes. Statins have anti-inflammatory activity beyond lowering lipid levels. We investigated the effects of ex-vivo and in-vivo atorvastatin treatment in acute coronary syndromes on CD4(+)T-cells, and the u...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Severino, Anna, Zara, Chiara, Campioni, Mara, Flego, Davide, Angelini, Giulia, Pedicino, Daniela, Giglio, Ada Francesca, Trotta, Francesco, Giubilato, Simona, Pazzano, Vincenzo, Lucci, Claudia, Iaconelli, Antonio, Ruggio, Aureliano, Biasucci, Luigi Marzio, Crea, Filippo, Liuzzo, Giovanna
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper: Pathology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392205/
https://ncbi.nlm.nih.gov/pubmed/28407684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15420
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