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Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers

NR5A2 (aka LRH-1) has been identified as a pancreatic cancer susceptibility gene with missing biological link. This study aims to demonstrate expression and potential role of NR5A2 in pancreatic cancer. NR5A2 expression was quantified in resected pancreatic ductal adenocarcinomas and the normal adja...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Carcinog
Hauptverfasser: Luo, Zhaofan, Li, Yanan, Mingxin, Zuo, Liu, Chang, Yan, Dong, Wang, Huamin, Li, Donghui
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392129/
https://ncbi.nlm.nih.gov/pubmed/27996162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22604
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