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Effect of NR5A2 inhibition on pancreatic cancer stem cell (CSC) properties and epithelial-mesenchymal transition (EMT) markers

NR5A2 (aka LRH-1) has been identified as a pancreatic cancer susceptibility gene with missing biological link. This study aims to demonstrate expression and potential role of NR5A2 in pancreatic cancer. NR5A2 expression was quantified in resected pancreatic ductal adenocarcinomas and the normal adja...

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Podrobná bibliografie
Vydáno v:Mol Carcinog
Hlavní autoři: Luo, Zhaofan, Li, Yanan, Mingxin, Zuo, Liu, Chang, Yan, Dong, Wang, Huamin, Li, Donghui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392129/
https://ncbi.nlm.nih.gov/pubmed/27996162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22604
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