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Loss of Rereplication Control in Saccharomyces cerevisiae Results in Extensive DNA Damage

To maintain genome stability, the entire genome of a eukaryotic cell must be replicated once and only once per cell cycle. In many organisms, multiple overlapping mechanisms block rereplication, but the consequences of deregulating these mechanisms are poorly understood. Here, we show that disruptin...

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Bibliografiske detaljer
Main Authors: Green, Brian M., Li, Joachim J.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC539184/
https://ncbi.nlm.nih.gov/pubmed/15537702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0833
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