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Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification
Eukaryotic cells use numerous mechanisms to ensure that no segment of their DNA is inappropriately re-replicated, but the importance of this stringent control on genome stability has not been tested. Here we show that re-replication in Saccharomyces cerevisiae can strongly induce the initial step of...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3700424/ https://ncbi.nlm.nih.gov/pubmed/20724634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1190966 |
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