The A78V Mutation in the Mad3-like Domain of Schizosaccharomyces pombe Bub1p Perturbs Nuclear Accumulation and Kinetochore Targeting of Bub1p, Bub3p, and Mad3p and Spindle Assembly Checkpoint Function

During mitosis, the spindle assembly checkpoint (SAC) responds to faulty attachments between kinetochores and the mitotic spindle by imposing a metaphase arrest until the defect is corrected, thereby preventing chromosome missegregation. A genetic screen to isolate SAC mutants in fission yeast yield...

Full beskrivning

Bibliografiska uppgifter

I publikationen:	Mol Biol Cell
Huvudupphov:	Kadura, Sheila, He, Xiangwei, Vanoosthuyse, Vincent, Hardwick, Kevin G., Sazer, Shelley
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Cell Biology 2005
Ämnen:	Articles
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15525673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-07-0558
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!