The A78V Mutation in the Mad3-like Domain of Schizosaccharomyces pombe Bub1p Perturbs Nuclear Accumulation and Kinetochore Targeting of Bub1p, Bub3p, and Mad3p and Spindle Assembly Checkpoint Function

During mitosis, the spindle assembly checkpoint (SAC) responds to faulty attachments between kinetochores and the mitotic spindle by imposing a metaphase arrest until the defect is corrected, thereby preventing chromosome missegregation. A genetic screen to isolate SAC mutants in fission yeast yield...

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Detalles Bibliográficos

Publicado en:	Mol Biol Cell
Principais autores:	Kadura, Sheila, He, Xiangwei, Vanoosthuyse, Vincent, Hardwick, Kevin G., Sazer, Shelley
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Cell Biology 2005
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC539181/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15525673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-07-0558
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