Loading...

T-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.

The severe combined immune deficient (scid) mouse mutant is characterized by a general absence of functional B and T lymphocytes. This deficiency appears to result from a defect in the variable-diversity-joining (VDJ) recombinase system, which is responsible for the assembly of V, D, and J gene segm...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Petrini, J H, Carroll, A M, Bosma, M J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53918/
https://ncbi.nlm.nih.gov/pubmed/2159151
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!