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T-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.

The severe combined immune deficient (scid) mouse mutant is characterized by a general absence of functional B and T lymphocytes. This deficiency appears to result from a defect in the variable-diversity-joining (VDJ) recombinase system, which is responsible for the assembly of V, D, and J gene segm...

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Detaylı Bibliyografya
Asıl Yazarlar: Petrini, J H, Carroll, A M, Bosma, M J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1990
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC53918/
https://ncbi.nlm.nih.gov/pubmed/2159151
Etiketler: Etiketle
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