Differential effect of an Ig μ transgene on development of pre-B cells in fetal and adult SCID mice

Progression of pro-B lymphocytes to the pre-B stage depends on the expression of a pre-B cell receptor (pre-BCR), consisting of an Ig μ H chain, Ig surrogate light chain, and associated signal transducing chains. Mice that are unable to express a pre-BCR show an arrest of B cell development at the p...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Bosma, Gayle C., Chang, Yung, Karasuyama, Hajime, Bosma, Melvin J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11952
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