Differential effect of an Ig μ transgene on development of pre-B cells in fetal and adult SCID mice

Progression of pro-B lymphocytes to the pre-B stage depends on the expression of a pre-B cell receptor (pre-BCR), consisting of an Ig μ H chain, Ig surrogate light chain, and associated signal transducing chains. Mice that are unable to express a pre-BCR show an arrest of B cell development at the p...

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Bibliografiska uppgifter
Huvudupphovsmän: Bosma, Gayle C., Chang, Yung, Karasuyama, Hajime, Bosma, Melvin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1999
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC18393/
https://ncbi.nlm.nih.gov/pubmed/10518557
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