Co-chaperone Hsp70/Hsp90-organizing protein (Hop) is required for transposon silencing and Piwi-interacting RNA (piRNA) biogenesis

Piwi-interacting RNAs (piRNAs) are 26–30-nucleotide germ line-specific small non-coding RNAs that have evolutionarily conserved function in mobile genetic element (transposons) silencing and maintenance of genome integrity. Drosophila Hsp70/90-organizing protein homolog (Hop), a co-chaperone, intera...

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Foilsithe in:J Biol Chem
Main Authors: Karam, Joseph A., Parikh, Rasesh Y., Nayak, Dhananjaya, Rosenkranz, David, Gangaraju, Vamsi K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2017
Ábhair:
Accelerated Communications
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391737/
https://ncbi.nlm.nih.gov/pubmed/28193840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C117.777730
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