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A critical role for nucleoporin 358 (Nup358) in transposon silencing and piRNA biogenesis in Drosophila

Piwi-interacting RNAs (piRNAs) are a class of small noncoding RNAs that bind Piwi proteins to silence transposons and to regulate gene expression. In Drosophila germ cells, the Aubergine (Aub)-Argonaute 3 (Ago3)–dependent ping-pong cycle generates most germline piRNAs. Loading of antisense piRNAs am...

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書目詳細資料
發表在:J Biol Chem
Main Authors: Parikh, Rasesh Y., Lin, Haifan, Gangaraju, Vamsi K.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005430/
https://ncbi.nlm.nih.gov/pubmed/29735528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.003264
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