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Gap Junctions Regulate Extracellular Signal-regulated Kinase Signaling to Affect Gene Transcription

Osteoblasts are highly coupled by gap junctions formed by connexin43. Overexpression of connexin45 in osteoblasts results in decreased chemical and electrical coupling and reduces gene transcription from connexin response elements (CxREs) in the osteocalcin and collagen Iα1 promoters. Here, we demon...

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Detalhes bibliográficos
Main Authors: Stains, Joseph P., Civitelli, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539152/
https://ncbi.nlm.nih.gov/pubmed/15525679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0339
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