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Gap Junctions Regulate Extracellular Signal-regulated Kinase Signaling to Affect Gene Transcription

Osteoblasts are highly coupled by gap junctions formed by connexin43. Overexpression of connexin45 in osteoblasts results in decreased chemical and electrical coupling and reduces gene transcription from connexin response elements (CxREs) in the osteocalcin and collagen Iα1 promoters. Here, we demon...

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Hlavní autoři: Stains, Joseph P., Civitelli, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC539152/
https://ncbi.nlm.nih.gov/pubmed/15525679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0339
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