Á lódáil...
Endogenous Brain Lipids Inhibit Prion Amyloid Formation In Vitro
The normal cellular prion protein (PrP(C)) resides in detergent-resistant outer membrane lipid rafts in which conversion to the pathogenic misfolded form is believed to occur. Once misfolding occurs, the pathogenic isoform polymerizes into highly stable amyloid fibrils. In vitro assays have demonstr...
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| Foilsithe in: | J Virol |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5391467/ https://ncbi.nlm.nih.gov/pubmed/28202758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02162-16 |
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