A Bivalent Heterologous DNA Virus-Like-Particle Prime-Boost Vaccine Elicits Broad Protection against both Group 1 and 2 Influenza A Viruses

Current seasonal influenza vaccines are efficacious when vaccine strains are matched with circulating strains. However, they do not protect antigenic variants and newly emerging pandemic and outbreak strains. Thus, there is a critical need for developing so-called “universal” vaccines that protect a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Jiang, Wenbo, Wang, Shuangshuang, Chen, Honglin, Ren, Huanhuan, Huang, Xun, Wang, Guiqin, Chen, Ze, Chen, Ling, Chen, Zhiwei, Zhou, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391461/
https://ncbi.nlm.nih.gov/pubmed/28179535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02052-16
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