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Transferrin-polycation conjugates as carriers for DNA uptake into cells.

We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic acids. Human transferrin, as well as the chicke...

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Detalhes bibliográficos
Main Authors: Wagner, E, Zenke, M, Cotten, M, Beug, H, Birnstiel, M L
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53910/
https://ncbi.nlm.nih.gov/pubmed/2333290
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