Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice

KEY POINTS: Late gestation during pregnancy has been associated with a relatively high prevalence of obstructive sleep apnoea (OSA). Intermittent hypoxia, a hallmark of OSA, could impose significant long‐term effects on somatic growth, energy homeostasis and metabolic function in offspring. Here we...

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Опубликовано в: :J Physiol
Главные авторы: Khalyfa, Abdelnaby, Cortese, Rene, Qiao, Zhuanhong, Ye, Honggang, Bao, Riyue, Andrade, Jorge, Gozal, David
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2017
Предметы:
Respiratory
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390895/
https://ncbi.nlm.nih.gov/pubmed/28090638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273570
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