Late gestational intermittent hypoxia induces metabolic and epigenetic changes in male adult offspring mice

KEY POINTS: Late gestation during pregnancy has been associated with a relatively high prevalence of obstructive sleep apnoea (OSA). Intermittent hypoxia, a hallmark of OSA, could impose significant long‐term effects on somatic growth, energy homeostasis and metabolic function in offspring. Here we...

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Bibliografische gegevens
Gepubliceerd in:J Physiol
Hoofdauteurs: Khalyfa, Abdelnaby, Cortese, Rene, Qiao, Zhuanhong, Ye, Honggang, Bao, Riyue, Andrade, Jorge, Gozal, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2017
Onderwerpen:
Respiratory
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390895/
https://ncbi.nlm.nih.gov/pubmed/28090638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273570
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