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Hypoxia and cellular metabolism in tumour pathophysiology

Cancer cells are optimised for growth and survival via an ability to outcompete normal cells in their microenvironment. Many of these advantageous cellular adaptations are promoted by the pathophysiological hypoxia that arises in solid tumours due to incomplete vascularisation. Tumour cells are thus...

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Detalles Bibliográficos
Publicado en:J Physiol
Main Authors: Parks, Scott K., Cormerais, Yann, Pouysségur, Jacques
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390873/
https://ncbi.nlm.nih.gov/pubmed/28074546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273309
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