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Fluorogenic sensor platform for the histone code using receptors from dynamic combinatorial libraries

Post-translational modifications (PTMs) on histone tails act in diverse combinations in the ‘histone code’ to control gene expression, with dysregulation observed in a variety of diseases. However, detection and sensing methods are limited, expensive, and/or low-throughput, including MS and antibody...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Peacor, Brendan C., Ramsay, Christopher M., Waters, Marcey L.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390788/
https://ncbi.nlm.nih.gov/pubmed/28451282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc03003c
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