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Proteolytic fingerprinting of complex biological samples using combinatorial libraries of fluorogenic probes

Proteases have garnered interest as candidate biomarkers and therapeutic targets for many human diseases. A key challenge is the identification and characterization of disease-relevant proteases in the complex milieu of biological fluids such as serum, plasma and bronchoalveolar lavage, in which a m...

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Detalhes bibliográficos
Main Authors: Jambunathan, Kalyani, Watson, Douglas S., Kodukula, Krishna, Galande, Amit K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518868/
https://ncbi.nlm.nih.gov/pubmed/23151745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471140864.ps2122s70
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