Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe

Redox imbalance in cells induces lipid peroxidation and generates a class of highly reactive metabolites known as lipid-derived electrophiles (LDEs) that can modify proteins and affects their functions. Identifying targets of LDEs is critical to understand how such modifications are functionally imp...

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Udgivet i:Redox Biol
Main Authors: Chen, Ying, Cong, Yan, Quan, Baiyi, Lan, Tong, Chu, Xiaoyu, Ye, Zi, Hou, Xiaomeng, Wang, Chu
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390668/
https://ncbi.nlm.nih.gov/pubmed/28411555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.04.001
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