Differential adipokine DNA methylation and gene expression in subcutaneous adipose tissue from adult offspring of women with diabetes in pregnancy

BACKGROUND: Offspring of women with diabetes in pregnancy are at increased risk of type 2 diabetes mellitus (T2DM), potentially mediated by epigenetic mechanisms. The adipokines leptin, adiponectin, and resistin (genes: LEP, ADIPOQ, RETN) play key roles in the pathophysiology of T2DM. We hypothesize...

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Bibliografiske detaljer
Udgivet i:Clin Epigenetics
Main Authors: Houshmand-Oeregaard, Azadeh, Hansen, Ninna S., Hjort, Line, Kelstrup, Louise, Broholm, Christa, Mathiesen, Elisabeth R., Clausen, Tine D., Damm, Peter, Vaag, Allan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
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Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390345/
https://ncbi.nlm.nih.gov/pubmed/28413567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0338-2
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