Topography of toxin-acetylcholine receptor complexes by using photoactivatable toxin derivatives.

We have defined the molecular environment of a snake neurotoxin interacting with the high- and low-affinity binding sites of the nicotinic acetylcholine receptor (AcChoR). This was done by photocoupling reactions using three toxin derivatives with photoactivatable moieties on Lys-15, Lys-47, and Lys...

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Bibliographische Detailangaben
Hauptverfasser: Chatrenet, B, Trémeau, O, Bontems, F, Goeldner, M P, Hirth, C G, Ménez, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53903/
https://ncbi.nlm.nih.gov/pubmed/2333287
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