Topography of toxin-acetylcholine receptor complexes by using photoactivatable toxin derivatives.

We have defined the molecular environment of a snake neurotoxin interacting with the high- and low-affinity binding sites of the nicotinic acetylcholine receptor (AcChoR). This was done by photocoupling reactions using three toxin derivatives with photoactivatable moieties on Lys-15, Lys-47, and Lys...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Chatrenet, B, Trémeau, O, Bontems, F, Goeldner, M P, Hirth, C G, Ménez, A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1990
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53903/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333287/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3378
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