Specificity, Privacy, and Degeneracy in the CD4 T Cell Receptor Repertoire Following Immunization

T cells recognize antigen using a large and diverse set of antigen-specific receptors created by a complex process of imprecise somatic cell gene rearrangements. In response to antigen-/receptor-binding-specific T cells then divide to form memory and effector populations. We apply high-throughput se...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Sun, Yuxin, Best, Katharine, Cinelli, Mattia, Heather, James M., Reich-Zeliger, Shlomit, Shifrut, Eric, Friedman, Nir, Shawe-Taylor, John, Chain, Benny
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5390035/
https://ncbi.nlm.nih.gov/pubmed/28450864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00430
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