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Induction of Host Matrix Metalloproteinases by Borrelia burgdorferi Differs in Human and Murine Lyme Arthritis

Matrix metalloproteinases (MMPs) are induced from host tissues in response to Borrelia burgdorferi. Upregulation of MMPs may play a role in the dissemination of the organism through extracellular matrix tissues, but it can also result in destructive pathology. Although mice are a well-accepted model...

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Detalhes bibliográficos
Main Authors: Behera, Aruna K., Hildebrand, Ethan, Scagliotti, Joanna, Steere, Allen C., Hu, Linden T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539001/
https://ncbi.nlm.nih.gov/pubmed/15618147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.126-134.2005
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