Depletion of Complement Has Distinct Effects on the Primary and Secondary Antibody Responses to a Conjugate of Pneumococcal Serotype 14 Capsular Polysaccharide and a T-Cell-Dependent Protein Carrier

Complement activation plays a critical role in the immune response to T-cell-dependent and T-cell-independent antigens. However, the effect of conjugation of T-cell-dependent protein carriers to T-cell-independent type 2 antigens on the requirement for complement in the humoral immune response to su...

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Bibliographic Details
Main Authors: Test, Samuel T., Mitsuyoshi, Joyce K., Hu, Yong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Microbial Immunity and Vaccines
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC538989/
https://ncbi.nlm.nih.gov/pubmed/15618164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.277-286.2005
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