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Oncogenic BRAF disrupts thyroid morphogenesis and function via twist expression
Thyroid cancer is common, yet the sequence of alterations that promote tumor formation are incompletely understood. Here, we describe a novel model of thyroid carcinoma in zebrafish that reveals temporal changes due to BRAF(V600E). Through the use of real-time in vivo imaging, we observe disruption...
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| 發表在: | eLife |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
eLife Sciences Publications, Ltd
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389860/ https://ncbi.nlm.nih.gov/pubmed/28350298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.20728 |
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