Impact of human monocyte and macrophage polarization on NLR expression and NLRP3 inflammasome activation

Inflammasomes are multiprotein complexes nucleating around an NLR (Nucleotide-binding domain and Leucine-rich Repeat containing protein), which regulate the secretion of the pro-inflammatory interleukin (IL)-1β and IL-18 cytokines. Monocytes and macrophages, the main cells expressing the inflammasom...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Awad, Fawaz, Assrawi, Eman, Jumeau, Claire, Georgin-Lavialle, Sophie, Cobret, Laetitia, Duquesnoy, Philippe, Piterboth, William, Thomas, Lucie, Stankovic-Stojanovic, Katia, Louvrier, Camille, Giurgea, Irina, Grateau, Gilles, Amselem, Serge, Karabina, Sonia-Athina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389804/
https://ncbi.nlm.nih.gov/pubmed/28403163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175336
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