β-Glucan–induced reprogramming of human macrophages inhibits NLRP3 inflammasome activation in cryopyrinopathies

Exposure of mononuclear phagocytes to β-glucan, a naturally occurring polysaccharide, contributes to the induction of innate immune memory, which is associated with long-term epigenetic, metabolic, and functional reprogramming. Although previous studies have shown that innate immune memory induced b...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Camilli, Giorgio, Bohm, Mathieu, Piffer, Alícia Corbellini, Lavenir, Rachel, Williams, David L., Neven, Benedicte, Grateau, Gilles, Georgin-Lavialle, Sophie, Quintin, Jessica
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456248/
https://ncbi.nlm.nih.gov/pubmed/32716363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI134778
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