Pasteurella multocida Toxin Activates Human Monocyte-Derived and Murine Bone Marrow-Derived Dendritic Cells In Vitro but Suppresses Antibody Production In Vivo

Pasteurella multocida toxin (PMT) is a potent mitogen for fibroblasts and osteoblastic cells. PMT activates phospholipase C-β through G(q)α, and the activation of this pathway is responsible for its mitogenic activity. Here, we investigated the effects of PMT on human monocyte-derived dendritic cell...

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Hlavní autoři: Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Lewis, George K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2005
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538973/
https://ncbi.nlm.nih.gov/pubmed/15618179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.413-421.2005
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