Cholera Toxin Indirectly Activates Human Monocyte-Derived Dendritic Cells In Vitro through the Production of Soluble Factors, Including Prostaglandin E(2) and Nitric Oxide

Cholera toxin (CT) is a potent adjuvant that activates dendritic cells (DC) by increasing intracellular cyclic AMP (cAMP) levels. In vivo and in vitro, very small amounts of CT induce potent adjuvant effects and activate DC. We hypothesized that DC intoxicated by CT may release factors that enhance...

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Hlavní autoři: Bagley, Kenneth C., Abdelwahab, Sayed F., Tuskan, Robert G., Lewis, George K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Cellular Immunology, Antibodies, and Mediators of Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356627/
https://ncbi.nlm.nih.gov/pubmed/16426007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.13.1.106-115.2006
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