RMI1 and TOP3α limit meiotic CO formation through their C-terminal domains

At meiosis, hundreds of programmed DNA double-strand breaks (DSBs) form and are repaired by homologous recombination. From this large number of DSBs, only a subset yields crossovers (COs), with a minimum of one CO per chromosome pair. All DSBs must be repaired and every recombination intermediate mu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Séguéla-Arnaud, Mathilde, Choinard, Sandrine, Larchevêque, Cécile, Girard, Chloé, Froger, Nicole, Crismani, Wayne, Mercier, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389728/
https://ncbi.nlm.nih.gov/pubmed/27965412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1210
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