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Gamma Interferon and Monophosphoryl Lipid A-Trehalose Dicorynomycolate Are Efficient Adjuvants for Mycobacterium tuberculosis Multivalent Acellular Vaccine

In this study, we examined the immunogenicity and protective efficacy of six immunodominant Mycobacterium tuberculosis recombinant antigens (85B, 38kDa, ESAT-6, CFP21, Mtb8.4, and 16kDa) in a multivalent vaccine preparation (6Ag). Gamma interferon (IFN-γ) and monophosphoryl lipid A-trehalose dicoryn...

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Detalhes bibliográficos
Main Authors: Hovav, Avi-Hai, Fishman, Yolanta, Bercovier, Herve
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC538970/
https://ncbi.nlm.nih.gov/pubmed/15618161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.250-257.2005
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