Gamma Interferon and Monophosphoryl Lipid A-Trehalose Dicorynomycolate Are Efficient Adjuvants for Mycobacterium tuberculosis Multivalent Acellular Vaccine

In this study, we examined the immunogenicity and protective efficacy of six immunodominant Mycobacterium tuberculosis recombinant antigens (85B, 38kDa, ESAT-6, CFP21, Mtb8.4, and 16kDa) in a multivalent vaccine preparation (6Ag). Gamma interferon (IFN-γ) and monophosphoryl lipid A-trehalose dicoryn...

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Bibliografiske detaljer
Main Authors: Hovav, Avi-Hai, Fishman, Yolanta, Bercovier, Herve
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538970/
https://ncbi.nlm.nih.gov/pubmed/15618161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.250-257.2005
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