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Role of Innate Immune Factors in the Adjuvant Activity of Monophosphoryl Lipid A

Monophosphoryl lipid A (MPL) is a nontoxic derivative of lipopolysaccharide (LPS) that exhibits adjuvant properties similar to those of the parent LPS molecule. However, the mechanism by which MPL initiates its immunostimulatory properties remains unclear. Due to the involvement of Toll-like recepto...

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Bibliografski detalji
Glavni autori: Martin, Michael, Michalek, Suzanne M., Katz, Jannet
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC153245/
https://ncbi.nlm.nih.gov/pubmed/12704121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2498-2507.2003
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