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Role of Innate Immune Factors in the Adjuvant Activity of Monophosphoryl Lipid A

Monophosphoryl lipid A (MPL) is a nontoxic derivative of lipopolysaccharide (LPS) that exhibits adjuvant properties similar to those of the parent LPS molecule. However, the mechanism by which MPL initiates its immunostimulatory properties remains unclear. Due to the involvement of Toll-like recepto...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Martin, Michael, Michalek, Suzanne M., Katz, Jannet
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2003
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC153245/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12704121/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.71.5.2498-2507.2003
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