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Role of Innate Immune Factors in the Adjuvant Activity of Monophosphoryl Lipid A

Monophosphoryl lipid A (MPL) is a nontoxic derivative of lipopolysaccharide (LPS) that exhibits adjuvant properties similar to those of the parent LPS molecule. However, the mechanism by which MPL initiates its immunostimulatory properties remains unclear. Due to the involvement of Toll-like recepto...

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Autors principals: Martin, Michael, Michalek, Suzanne M., Katz, Jannet
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153245/
https://ncbi.nlm.nih.gov/pubmed/12704121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.5.2498-2507.2003
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