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Translational compensation of gene copy number alterations by aneuploidy in Drosophila melanogaster

Chromosomal or segmental aneuploidy—the gain or loss of whole or partial chromosomes—is typically deleterious for organisms, a hallmark of cancers, and only occasionally adaptive. To understand the cellular and organismal consequences of aneuploidy, it is important to determine how altered gene dose...

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Pubblicato in:Nucleic Acids Res
Autori principali: Zhang, Zhenguo, Presgraves, Daven C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389667/
https://ncbi.nlm.nih.gov/pubmed/28199687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx106
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