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A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N(4)-ethenocytosine
Etheno (ε) DNA base adducts are highly mutagenic lesions produced endogenously via reactions with lipid peroxidation (LPO) products. Cancer-promoting conditions, such as inflammation, can induce persistent oxidative stress and increased LPO, resulting in the accumulation of ε-adducts in different ti...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5389632/ https://ncbi.nlm.nih.gov/pubmed/28115629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx015 |
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