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Unusual C΄/D΄ motifs enable box C/D snoRNPs to modify multiple sites in the same rRNA target region

Eukaryotic box C/D small nucleolar (sno)RNPs catalyse the site-specific 2΄-O-methylation of ribosomal RNA. The RNA component (snoRNA) contains guide regions that base-pair with the target site to select the single nucleotide to be modified. The terminal C/D and internal C΄/D΄ motifs in the snoRNA, a...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: van Nues, Robert Willem, Watkins, Nicholas James
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389607/
https://ncbi.nlm.nih.gov/pubmed/28204564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw842
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