Specialized box C/D snoRNPs act as antisense guides to target RNA base acetylation

Box C/D snoRNAs are known to guide site-specific ribose methylation of ribosomal RNA. Here, we demonstrate a novel and unexpected role for box C/D snoRNAs in guiding 18S rRNA acetylation in yeast. Our results demonstrate, for the first time, that the acetylation of two cytosine residues in 18S rRNA...

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Publicat a:PLoS Genet
Autors principals: Sharma, Sunny, Yang, Jun, van Nues, Rob, Watzinger, Peter, Kötter, Peter, Lafontaine, Denis L. J., Granneman, Sander, Entian, Karl-Dieter
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464676/
https://ncbi.nlm.nih.gov/pubmed/28542199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006804
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