Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript

Muscleblind-like proteins (MBNLs) are regulators of RNA metabolism. During tissue differentiation the level of MBNLs increases, while their functional insufficiency plays a crucial role in myotonic dystrophy (DM). Deep sequencing of RNA molecules cross-linked to immunoprecipitated protein particles...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Konieczny, Patryk, Stepniak-Konieczna, Ewa, Taylor, Katarzyna, Sznajder, Łukasz J., Sobczak, Krzysztof
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389549/
https://ncbi.nlm.nih.gov/pubmed/27903900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1158
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