Mechanistic determinants of MBNL activity

Muscleblind-like (MBNL) proteins are critical RNA processing factors in development. MBNL activity is disrupted in the neuromuscular disease myotonic dystrophy type 1 (DM1), due to the instability of a non-coding microsatellite in the DMPK gene and the expression of CUG expansion (CUG(exp)) RNAs. Pa...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Sznajder, Łukasz J., Michalak, Michał, Taylor, Katarzyna, Cywoniuk, Piotr, Kabza, Michał, Wojtkowiak-Szlachcic, Agnieszka, Matłoka, Magdalena, Konieczny, Patryk, Sobczak, Krzysztof
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137450/
https://ncbi.nlm.nih.gov/pubmed/27733504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw915
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares