Mechanistic determinants of MBNL activity

Muscleblind-like (MBNL) proteins are critical RNA processing factors in development. MBNL activity is disrupted in the neuromuscular disease myotonic dystrophy type 1 (DM1), due to the instability of a non-coding microsatellite in the DMPK gene and the expression of CUG expansion (CUG(exp)) RNAs. Pa...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Sznajder, Łukasz J., Michalak, Michał, Taylor, Katarzyna, Cywoniuk, Piotr, Kabza, Michał, Wojtkowiak-Szlachcic, Agnieszka, Matłoka, Magdalena, Konieczny, Patryk, Sobczak, Krzysztof
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Molecular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137450/
https://ncbi.nlm.nih.gov/pubmed/27733504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw915
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