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Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma

Drug resistance has always been the main problem in osteosarcoma treatment, and hypoxia seems to be one of the many causes for drug resistance. Therefore, in this study, we investigated how hypoxia triggers chemotherapy resistance in osteosarcoma. We first screened hypoxia- and normoxia- cultured os...

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Detalles Bibliográficos
Publicado en:Cancer Biol Ther
Main Authors: Ma, Qiong, Zhang, Yinglong, Liu, Tao, Jiang, Kuo, Wen, Yanhua, Fan, Qingyu, Qiu, Xiuchun
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389426/
https://ncbi.nlm.nih.gov/pubmed/28278080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1294285
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