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Hypoxia promotes chemotherapy resistance by down-regulating SKA1 gene expression in human osteosarcoma

Drug resistance has always been the main problem in osteosarcoma treatment, and hypoxia seems to be one of the many causes for drug resistance. Therefore, in this study, we investigated how hypoxia triggers chemotherapy resistance in osteosarcoma. We first screened hypoxia- and normoxia- cultured os...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Ma, Qiong, Zhang, Yinglong, Liu, Tao, Jiang, Kuo, Wen, Yanhua, Fan, Qingyu, Qiu, Xiuchun
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389426/
https://ncbi.nlm.nih.gov/pubmed/28278080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2017.1294285
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