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PEST Control of Molecular Stripping of NFκB from DNA Transcription Sites

We recently proposed a model for the IκBα-mediated molecular stripping of NFκB from transcription sites. IκBα was shown experimentally to form a transient ternary complex with DNA-bound NFκB, but the mechanism by which the IκBα accelerates dissociation of the NFκB from the DNA was unknown. In this p...

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Vydáno v:J Phys Chem B
Hlavní autoři: Potoyan, Davit A., Zheng, Weihua, Ferreiro, Diego U., Wolynes, Peter G., Komives, Elizabeth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389414/
https://ncbi.nlm.nih.gov/pubmed/27098223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b02359
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