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Reduced Local Growth and Spread but Preserved Pathogenicity of a ΔpurC Mycobacterium tuberculosis Auxotrophic Mutant in Gamma Interferon Receptor-Deficient Mice after Aerosol Infection
We compared the growth levels and pathogenicities of the Mycobacterium tuberculosis MT103 clinical strain with those of the ΔpurC mutant strain MYC1551, which is auxotrophic for purine in wild-type and gamma interferon receptor (IFN-γR)-deficient mice. The ΔpurC strain MYC1551 grew initially in both...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538938/ https://ncbi.nlm.nih.gov/pubmed/15618214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.666-670.2005 |
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