Reduced Local Growth and Spread but Preserved Pathogenicity of a ΔpurC Mycobacterium tuberculosis Auxotrophic Mutant in Gamma Interferon Receptor-Deficient Mice after Aerosol Infection

We compared the growth levels and pathogenicities of the Mycobacterium tuberculosis MT103 clinical strain with those of the ΔpurC mutant strain MYC1551, which is auxotrophic for purine in wild-type and gamma interferon receptor (IFN-γR)-deficient mice. The ΔpurC strain MYC1551 grew initially in both...

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Bibliografski detalji
Glavni autori: Brown, Najmeeyah, Jacobs, Muazzam, Parida, Shreemanta K., Botha, Tania, Santos, Aldina, Fick, Lizette, Gicquel, Brigitte, Jackson, Mary, Quesniaux, Valerie, Ryffel, Bernhard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Microbial Immunity and Vaccines
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC538938/
https://ncbi.nlm.nih.gov/pubmed/15618214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.1.666-670.2005
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